A couple of glass of alcohol won't hurt, while you are taking doxycycline. Just separate the dose from when you drink alcohol, to ensure that the antibiotic is absorbed properly. Drinking Beer While Taking Doxycycline | NoPrescriptionPharmacy. Complete Drinking Beer While Taking Doxycycline Packaging and Shipping Supplies, Inc (Complete Packaging), is a leading provider of integrated supply, procurement and logistics solutions through distribution of a diverse range of products and services worldwide. Is it OK if I have a few beers while I'm taking Doxycycline 100mg twice a day? I'm not getting wasted or anything, I just want to have a few with the guys this Friday. I'm not getting wasted or anything, I just want to have a few with the guys this Friday. Taking antibiotics with alcohol. In general, drinking any amount of alcohol while fighting an infection may not be wise, as it can lead to dehydration, interrupt normal sleep, and may hinder the body’s natural ability to heal itself. Regular alcohol consumption has been shown to decrease the effectiveness of doxycycline, a commonly prescribed antibiotic used to treat a wide variety of infections. Even if a doctor hasn’t been consulted, a patient who is taking doxycycline could possibly drink small amounts, approximately equal to one or two glasses of wine or cans of beer per day with minimal negative effects, if that alcohol is generally consumed very slowly. It's sensible to avoid drinking alcohol when taking medication or feeling unwell. But it's unlikely that drinking alcohol in moderation will cause problems if you're taking most common antibiotics. Taking Doxycycline and alcohol together can, therefore, cause stomach pain, cramps, diarrhea, and vomiting. As we all know, alcohol neutralizes the effects of many medicine types on the market. Drinking while on Doxycycline is no exception. Alcohol and Doxycycline. While alcohol is not prohibited while being treated with doxycycline it is also no recommended. While one to two drinks will not cause adverse effects, if you binge drink or are a chronic alcohol drinker the effectiveness of the medication can be lessened. Doxycycline is a class of medications called tetracycline antibiotics and is used to treat bacterial infections such as respiratory infections like pneumonia, malaria, Lyme disease, acne, bacterial skin infections, genital and urinary infections and inhaled anthrax disease.